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Alternate Names Leukocyte adhesion receptor p150+,  CD11 antigen-like family member C,  CD11c,  Integrin alpha-X,  Leukocyte adhesion receptor p150+95,  Itgax,  p150-95,   CR4,   integrin &,  alpha-X-X
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Verified Samples Verified Samples in FCM: C57/BL6 Mouse splenocytes
Dilution FCM 2 μg/mL(0.5×106-1×106 cells)
Background CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen, and CD54.
Immunogen Recombinant Mouse CD11c protein
Abbre CD11c
Swissprot
Host Armenian Hamster
Reactivity Mouse
Clonality Monoclonal
Purification Method >98%, Protein A/G purified
Isotype Armenian Hamster IgG
Isotype Control Purified Armenian Hamster IgG Isotype Control[PIP]
Applications
FCM
Concentration
≥ 1 mg/mL
Conjugation Unconjugated
Storage Buffer Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Storage Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Expiration Date 12 months
Shipping Ice bag
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